Blastocyst Transfer

Thousands of couples every year opt to go through IVF fertility treatment in order to increase their chances of conception. If you and your partner are considering an IVF procedure, then you may have heard of many successful procedures performed using blastocyst transfer. Blastocyst transfer is becoming more and more popular in North American fertility clinics, and may help you to increase your chances of IVF success. What is Blastocyst Transfer?

Blastocyst transfer is a type of embryo transfer procedure used during IVF. This type of transfer was first performed 30 years ago and is now being used in an increasing number of fertility clinics. During this type of transfer, a blastocyst embryo is placed inside of your uterus where it will hopefully implant and develop into a fetus. It is now becoming a popular alternative to Day 3 embryo transfer.

What is a Blastocyst?

A blastocyst is formed when an embryo reaches the five to seven-day development stage. At this point in development, the embryo has between 60 and 100 cells distributed in two areas: an outer embryo lining (which will later form the placenta), and an inner mass (which will later become the fetus). During a natural cycle, the embryo develops into the blastocyst stage as it is leaving the fallopian tubes and entering the uterus. An embryo needs to have entered into the blastocyst stage once it arrives in the uterus to ensure proper implantation.

How Many Embryos are Transferred?

hould you decide on a blastocyst transfer, it is likely that only one or two of your embryos will be transferred into your uterus. Fewer embryos are required for this type of transfer because blastocyst embryos are more likely to implant and develop than Day 3 embryos. Typically, between two and four embryos need to be transferred during a day 3 transfer procedure.

Disadvantages of Blastocyst Transfer

Blastocyst transfer does have a few disadvantages associated with it:

• Difficulty: Blastocyst culture is very difficult to do and requires a fully-equipped laboratory and intensive management. In order to survive the culture process, embryos need to be kept at specific temperatures and exposed to just the right culture medium. Some fertility clinics have not yet perfected this culture process and, as a result, have lower success rates.
• Loss of Embryos: If you choose to have a blastocyst transfer, expect to lose quite a few of your embryos. On average, up to 50% of embryos die before the blastocyst stage, but some couples lose more than half of their embryos.
• Freezing Difficulties: Many couples opt to pursue cryopreservation of any leftover embryos so that they can use them for fertility procedures in the future. Unfortunately, blastocysts do not survive the freezing process as well as Day 3 embryos do, so this may not be a option for you.